Clinical Data

European Journal of Pharmacology 644

7-hydroxyfrullanolide, a sesquiterpene lactone, inhibits pro-inflammatory cytokine production from immune cells and is orally efficacious in animal models of inflammation

European Journal of Pharmacology 657

NF-κB-mediated anti-inflammatory activity of the sesquiterpene lactone 7-hydroxyfrullanolide

Natural Supplements Research

The 3rd annual Natural Supplements Research Competition was hosted by the Scripps Center for Integrative Medicine on January 18–20, 2006, in La Jolla, CA, and took place as part of the conference “Natural Supplements: An Evidence Based Update.” This Continuing Medical Education conference, which was cosponsored by the Scripps Clinic and the University of California at San Diego (both in La Jolla) brought together a group of more than 400 health care providers to discuss emerging trends in the field of dietary supplements.

Nutrition & Metabolism

A novel anti-inflammatory natural product from Sphaeranthus indicus inhibits expression of VCAM1 and ICAM1, and slows atherosclerosis progression independent of lipid changes

Pharmacology & Pharmacy

NPS31807, a Standardized Extract from Sphaeranthus indicus, Inhibits Inflammatory, Migratory and Proliferative Activity in Keratinocytes and Immune Cells

American Academy of Dermatology

Sphaeranthus indicus (East India globe thistle)-a promising natural remedy for psoriasis by Somesh Sharma, Phd, Piramal Life Science, Mumbai, Maharashtra, India.

Phase II - Clinical Trial

Efficacy and Safety of Two Doses of Sphaeranthus indicus Extract in the Management of Plaque Psoriasis: A Randomized, Double Blind, Placebo Controlled Phase II Trial.

Phase IV - Clinical Trial

Efficacy and Safety of tinefcon® Tablets in Subjects with Plaque Psoriasis: An Open Label, Non-Comparative, Multicenter, Phase IV Trial.

tinefcon - Piramal

Articles describing parts of sphaeranthus indicus containing active fraction have been accepted for publication in Herbal Medicines Compendium of USP.